HelioLiver LDT now available to order through Quest Diagnostics
A warm healthcare professional ready to answer patient questions about liver health
HelioLiver™ LDT · For Patients

Get Answers About Your Liver

The HelioLiver test helps you learn about your risk for liver cancer and stay proactive about your care. It's a simple blood test for liver cancer screening, now available for clinical use as a laboratory-developed test (LDT).

Why Early Detection Matters

Why Is Early Detection of Liver Cancer So Important?

Liver cancer often hides. Symptoms may not appear until later stages, when it's harder to treat. The earlier liver cancer is found, the more treatment options you have and the better the chances of a good outcome. That's why routine liver cancer screening matters so much for people at higher risk.

Today's standard screening methods can't always detect liver cancer in its earliest stages. If you've been told you're at higher risk, keeping up with routine testing gives you the best chance of catching it early.

Less than half
of all liver cancers are diagnosed before the cancer has spread.
HelioLiver LDT Collection Kit box
What Is HelioLiver

Introducing the HelioLiver LDT, a Simple Blood Test for Liver Cancer

The HelioLiver laboratory-developed test is a blood test for liver cancer shown in clinical trials to detect hepatocellular carcinoma (HCC) in its early stages. With a simple blood draw during a routine visit, HelioLiver gives you and your doctor additional information to support early detection. HelioLiver does not replace the surveillance imaging your doctor recommends.

Why HelioLiver

Simple, Clinically Studied, and Readily Available

Simple

Just one simple blood draw during a routine doctor's visit.

Clinically Studied

In the CLiMB study, HelioLiver detected more liver cancers than ultrasound, with simple, easy-to-understand results.

Readily Available

We bill most commercial insurances and offer self-pay and assistance options. Talk with your physician about HelioLiver, and contact us with any questions about cost.

Who Is the Test For

Who Should Be Screened for Liver Cancer?

HelioLiver is designed for adults at higher risk of liver cancer, most often people with cirrhosis or chronic liver disease. You may be at higher risk if you have:

Cirrhosis from any cause

Chronic hepatitis B or hepatitis C

Alcohol-related liver disease

Fatty liver disease (MASLD / NAFLD)

Other liver conditions linked to higher cancer risk, such as hereditary hemochromatosis, primary biliary cholangitis, or Wilson's disease

HelioLiver is available by a doctor's order. If you think you may be at risk, talk to your doctor about whether liver cancer screening with HelioLiver is right for you.

How Often to Get Screened

How Often Should You Be Tested for Liver Cancer?

~6
months
AASLD Guidelines

For people at high risk of liver cancer, expert guidelines (AASLD) recommend surveillance about every six months. Because liver cancer can develop between visits, keeping up with regular testing is one of the most important things you can do to catch it early. Your doctor will recommend the right schedule for you, and HelioLiver is designed to fit easily into that routine as a simple blood draw.

Get in Touch

Get in Touch

Have questions about liver cancer screening or the HelioLiver test? Fill out this short form, and someone from the HelioLiver team will be in touch.

HelioLiver Team

Send us a message

By submitting, you agree to be contacted by the HelioLiver team about your inquiry.

The HelioLiver test is a laboratory developed test intended to aid in the detection of hepatocellular carcinoma in adults at high risk. It is not a replacement for guideline-recommended surveillance imaging and it is not a diagnostic test. A positive result requires diagnostic follow-up. A negative result does not exclude the presence of hepatocellular carcinoma.